Accumulation of 1,2-sn-diradylglycerol with increased membrane-associated protein kinase C may be the mechanism for spontaneous hepatocarcinogenesis in choline-deficient rats.

This publication has 73 references indexed in Scilit:

• Inhibition of phosphatidic acid phosphohydrolase activity by sphingosine
  FEBS Letters, 1990
• Choline deficiency activates phospholipases A2 and C in rat liver without affecting the activity of protein kinase C
  The Journal of Nutritional Biochemistry, 1990
• Direct evidence that the kinase activity of protein kinase C is involved in transcriptional activation through a TPA‐responsive element
  FEBS Letters, 1989
• Defect in phorbol acetate‐induced translocation of diacylglycerol kinase in erbB‐transformed fibroblast cells
  FEBS Letters, 1989
• 1,2-sn-Diacylglycerol accumulates in choline-deficient liver
  FEBS Letters, 1989
• Alkyl analogs of diacylglycerol as activators of protein kinase C
  FEBS Letters, 1987
• Structural and chemical specificity of diradylglycerols for protein kinase C activation
  Biochemical and Biophysical Research Communications, 1984
• Hepatocarcinogenesis in rats fed methyl-deficient, amino acid-defined diets
  Carcinogenesis, 1983
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
  Analytical Biochemistry, 1976
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
  Nature, 1970