Automated Determination of Serum Ceruloplasmin Activity with o-Dianisidine Dihydrochloride as Substrate

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Abstract
An automated method for the enzymatic determination of ceruloplasmin with o-dianisidine dihydrochioride as substrate is described. The method enables the measurement of 30 samples per hour with a coefficient of variation (day-to-day) of 2.8%. Results correlate well (r = 0.99) with those obtained by the corresponding manual method.