Discovery of 3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)-N-phenylpiperidine-1-carboxamide as novel potent analgesic

This publication has 53 references indexed in Scilit:

• A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine
  The Journal of Pharmacology and Experimental Therapeutics, 2013
• Pharmacological Characterization of ATPM [(-)-3-Aminothiazolo[5,4-b]-N-cyclopropylmethylmorphinan hydrochloride], a Novel Mixed κ-Agonist and μ-Agonist/-Antagonist That Attenuates Morphine Antinociceptive Tolerance and Heroin Self-Administration Behavior
  The Journal of Pharmacology and Experimental Therapeutics, 2009
• Benefits of Extended‐Release Opioid Analgesic Formulations in the Treatment of Chronic Pain
  Pain Practice, 2009
• Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate-to-severe noncancer pain
  Current Medical Research and Opinion, 2008
• Models of Nociception: Hot‐Plate, Tail‐Flick, and Formalin Tests in Rodents
  Current Protocols in Neuroscience, 2007
• Respiratory Depression with Opioids
  Journal of Pain & Palliative Care Pharmacotherapy, 2007
• Morphine Side Effects in β-Arrestin 2 Knockout Mice
  The Journal of Pharmacology and Experimental Therapeutics, 2005
• Toleranzentwicklung unter Opioidgabe - Molekulare Mechanismen und klinische Bedeutung
  AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie, 2003
• Design of peptidomimetic .delta. opioid receptor antagonists using the message-address concept
  Journal of Medicinal Chemistry, 1990
• Bivalent ligands and the message-address concept in the design of selective opioid receptor antagonists
  Trends in Pharmacological Sciences, 1989