Intraoperative Chemohyperthermia in the Management of Digestive Cancers

Authors:
  • ASA.C. Sayag
    A.C. Sayag
  • FGF.N. Gilly
    F.N. Gilly
  • PCP.Y. Carry
    P.Y. Carry
  • JPJ.P. Perdrix
    J.P. Perdrix
  • GPG. Panteix
    G. Panteix
  • ABA. Brachet
    A. Brachet
  • VBV. Banssillon
    V. Banssillon
  • GBG. Braillon
    G. Braillon
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Abstract
Intraoperative chemohyperthermia is a new method in the treatment of peritoneal seedings from digestive cancers, which combines surgery, intraperitoneal chemotherapy (mitomycin C and/or cisplatyl) and peritoneal hyperthermia. After a brief reminder on the general principles concerning high temperature action, a review of literature is made: 5 teams have performed this technique. We differentiate the indications, design features and results of each team. The results show a mean survival after 2 years of 35% (in peritoneal carcinomatosis) up to 78% (in gastric serosal invasion, peritoneal seeding free). The best result of the method is the drying up of cancerous ascites, allowing a more comfortable survival.