Successful Renal Artery Denervation in a Renal Transplant Recipient With Refractory Hypertension

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Abstract
Arterial hypertension in renal transplant recipients is the main risk factor of cardiovascular diseases, which remain the primary cause of death in patients with a functioning renal graft.1,2 The risk of cardiovascular death is four times higher in patients with kidney transplants compared with the general population.3 In renal transplant recipients, a 10-mm Hg rise in systolic blood pressure increases the risks of death by 18% and increases the risk of graft failure by 17%.4 The existing literature indicates that 70%–90% of kidney transplantation recipients experience arterial hypertension, which is a nonimmunological risk factor for premature graft failure.5–7 Notably, this serious risk factor is treatment resistant in every fifth patient. Recently published data suggest that 34.2% of graft recipients require the use of three drugs for hypertension treatment and that 30.6% require four or more concomitant hypotensive agents.8

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