Role of endogenous pain modulation in chronic pain mechanisms and treatment
Top Cited Papers
- 1 April 2015
- journal article
- review article
- Published by Wolters Kluwer Health in Pain
- Vol. 156 (Supplement) , S24-S31
Abstract
Development and application of psychophysical test paradigms to assess endogenous pain modulation in healthy controls and in patients yielded large body of data over the last 2 decades. These tests can assist in predicting pain acquisition, in characterizing pain syndromes and related dysfunctions of pain modulation, and in predicting response to treatment. This chapter reviews the development of thought on pain modulation in the clinical setup, focusing on conditioned pain modulation, and update on accumulated data regarding the mechanism, protocols of administration, and applications in the clinic.Keywords
This publication has 87 references indexed in Scilit:
- Age-Dependent Decline of Endogenous Pain Control: Exploring the Effect of Expectation and DepressionPLOS ONE, 2013
- Quantitative Sensory Testing Predicts Pregabalin Efficacy in Painful Chronic PancreatitisPLOS ONE, 2013
- Effects of Pregabalin on Central Sensitization in Patients with Chronic Pancreatitis in a Randomized, Controlled TrialPLOS ONE, 2012
- Normalization of widespread hyperesthesia and facilitated spatial summation of deep‐tissue pain in knee osteoarthritis patients after knee replacementArthritis & Rheumatism, 2012
- Sensitization in patients with painful knee osteoarthritisPain, 2010
- The methodology of experimentally induced diffuse noxious inhibitory control (DNIC)-like effect in humansPain, 2009
- Deficiency in endogenous modulation of prolonged heat pain in patients with Irritable Bowel Syndrome and Temporomandibular DisorderPain, 2009
- Offset analgesia: A temporal contrast mechanism for nociceptive informationPain, 2008
- Temporal Summation of Second Pain and Its Maintenance Are Useful for Characterizing Widespread Central Sensitization of Fibromyalgia PatientsThe Journal of Pain, 2007
- Striving for normality: whole body regeneration through a series of abnormal generationsThe FASEB Journal, 2007