Using hominin introgression to trace modern human dispersals
- 12 July 2019
- journal article
- research article
- Published by National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 116 (31) , 15327-15332
Abstract
The dispersal of anatomically modern human populations out of Africa and across much of the rest of the world around 55 to 50 thousand years before present (ka) is recorded genetically by the multiple hominin groups they met and interbred with along the way, including the Neandertals and Denisovans. The signatures of these introgression events remain preserved in the genomes of modern-day populations, and provide a powerful record of the sequence and timing of these early migrations, with Asia proving a particularly complex area. At least 3 different hominin groups appear to have been involved in Asia, of which only the Denisovans are currently known. Several interbreeding events are inferred to have taken place east of Wallace’s Line, consistent with archaeological evidence of widespread and early hominin presence in the area. However, archaeological and fossil evidence indicates archaic hominins had not spread as far as the Sahul continent (New Guinea, Australia, and Tasmania), where recent genetic evidence remains enigmatic.Keywords
Funding Information
- Australian Research Council (IN180100017)
- Australian Research Council (FL140100260)
This publication has 47 references indexed in Scilit:
- The complete genome sequence of a Neanderthal from the Altai MountainsNature, 2013
- Did the Denisovans Cross Wallace's Line?Science, 2013
- Higher Levels of Neanderthal Ancestry in East Asians than in EuropeansGenetics, 2013
- A High-Coverage Genome Sequence from an Archaic Denisovan IndividualScience, 2012
- Denisova Admixture and the First Modern Human Dispersals into Southeast Asia and OceaniaThe American Journal of Human Genetics, 2011
- New evidence for a 67,000-year-old human presence at Callao Cave, Luzon, PhilippinesJournal of Human Evolution, 2010
- A Draft Sequence of the Neandertal GenomeScience, 2010
- The complete mitochondrial DNA genome of an unknown hominin from southern SiberiaNature, 2010
- Mapping Human Genetic Diversity in AsiaScience, 2009
- Possible Ancestral Structure in Human PopulationsPLOS Genetics, 2006