Successful Treatment of Human Immunodeficiency Virus-Related Castleman’s Disease: A Case Report and Literature Review
Authors:
- Evagelos LiberopoulosEvagelos Liberopoulos
- Christos TolisCTChristos Tolis
- Mary BaiMBMary Bai
- Stavros EfremidisSEStavros Efremidis
- Nikolaos PavlidisNPNikolaos Pavlidis
- Moses ElisafMEMoses Elisaf
- 1 August 2003
- journal article
- case report
- Published by S. Karger AG in Oncology
- Vol. 65 (2) , 182-186
Abstract
Multicentric Castleman’s disease is increasingly recognized as an aggressive illness with a rapidly fatal outcome in human immunodeficiency virus (HIV)-infected patients. In the absence of optimal therapy, various therapeutic interventions have been tested with disappointing results; only five reports with a successful outcome have been described. Presented herein is a 66-year-old HIV-infected man with multicentric Castleman’s disease. Early administration of cyclophosphamide, doxorubicin, vincristine and prednisone resulted in prolonged clinical recovery. The relevant literature is also reviewed.Keywords
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