Plasma Viremia in Human Immunodeficiency Virus Infection
Authors:
- Ann C. CollierACAnn C. Collier
- Jean-P. AllainJAJean-P. Allain
- Beverly NikoraBNBeverly Nikora
- Michael LeutherMLMichael Leuther
- George F. GjersetGGGeorge F. Gjerset
- Lawrence CoreyLCLawrence Corey
- 14 December 1989
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 321 (24) , 1626-1631
Abstract
To determine which markers of human immunodeficiency virus type 1 (HIV) replication correlate most closely with progressive disease, we compared the following: (1) the frequency of isolation of HIV from peripheral-blood mononuclear cells (PBMC), (2) the frequency of isolation of the virus from cell-free plasma (plasma viremia), (3) the presence and titer of p24 antigen in plasma, and (4) the presence and titer of antibody to p24 antigen. We studied 213 persons who were positive for HIV antibody and 71 who were negative.Keywords
This publication has 27 references indexed in Scilit:
- Efficient isolation of HIV from plasma during different stages of HIV infectionJournal of Medical Virology, 1988
- Human Immunodeficiency Virus Antigenemia in Patients with AIDS and AIDS-Related Disorders: A Comparison Between European and Central African PopulationsThe Journal of Infectious Diseases, 1987
- Isolation of human immunodeficiency virus from hemophiliacs: Correlation with clinical symptoms and immunologic abnormalitiesThe Journal of Pediatrics, 1987
- Long-Term Evaluation of HIV Antigen and Antibodies to p24 and gp41 in Patients with HemophiliaNew England Journal of Medicine, 1987
- Correlation of serum HIV antigen and antibody with clinical status in HIV‐I infected patientsJournal of Medical Virology, 1987
- HIV ANTIGENAEMIA AND VIRUS ISOLATION FROM PLASMA DURING PRIMARY HIV INFECTIONThe Lancet, 1987
- HIV ANTIGEN TESTINGThe Lancet, 1987
- Persistent HIV antigenaemia and decline of HIV core antibodies associated with transition to AIDS.BMJ, 1986
- SEROLOGICAL MARKERS IN EARLY STAGES OF HUMAN IMMUNODEFICIENCY VIRUS INFECTION IN HAEMOPHILIACSThe Lancet, 1986
- Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDSScience, 1984