Stroke volume analog on a chip – in vitro hydrodynamic model of cardiac pumping efficiency
- 23 February 2026
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Lab on a Chip
- Vol. 26 (9) , 2720-2733
Abstract
We demonstrate the use of muscular thin films (MTFs) as a hydrodynamic assay to measure cardiac stroke volume on a chip, and quantify changes in response to ionotropic dosing; helping bridge the gap between in vitro and in vivo measurements.Keywords
Funding Information
- American Chemical Society (Irving S. Sigal Postdoctoral Fellowship)
- National Center for Advancing Translational Sciences (UH3 TR003279)
- National Heart, Lung, and Blood Institute (T32HL007572)
- NTT Research
- National Institutes of Health (UH3 TR003279)
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