High dose methylprednisolone in the immediate management of acute, blunt spinal cord injury: what is the current practice in emergency departments, spinal units, and neurosurgical units in the UK?
Author:
- 1 July 2006
- journal article
- Published by BMJ in Emergency Medicine Journal
- Vol. 23 (7) , 550-553
Abstract
The National Acute Spinal Cord Injuries Studies and the Cochrane Review advocate the administration of high dose methylprednisolone following acute traumatic spinal cord injury. However, controversy surrounds its use and approaches between different units are often inconsistent. A questionnaire was sent to all emergency departments receiving major trauma and all specialist neurosurgical and spinal units in the UK to determine the current practice regarding the use of high dose methylprednisolone in the immediate management of acute, blunt spinal cord injuries. Of 250 emergency departments, 187 replied to the questionnaire. Twelve of the 26 departments with a neurosurgical or spinal service on site stated they received consistent advice from specialist teams. Sixty four departments had a written policy regarding the treatment of spinal injuries, which in 51 departments contained advice about the administration of methylprednisolone. Of the 128 departments who gave methylprednisolone, 88 did so only on the advice of a specialist team, with the remaining 40 giving steroids immediately on identification of the injury. Ten out of 11 spinal units replied, of whom only two advised the used of steroids. Of the 34 neurosurgical units approached, seven out of 17 responders had a policy recommending the use of steroids. Of the 10 units who did not consistently recommend the use of steroids, seven had practise that varied between consultants. Currently practice varies in the UK regarding the immediate use of methylprednisolone after spinal injury. Clear guidelines need to be established to achieve a more consistent approach.Keywords
This publication has 19 references indexed in Scilit:
- Failure to administer methylprednisolone for acute traumatic spinal cord injury—a prospective audit of 100 patients from a regional spinal injuries unitInjury, 2002
- High-Dose Methylprednisolone for Acute Closed Spinal Cord Injury - Only a Treatment OptionCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2002
- Pharmacological Therapy after Acute Cervical Spinal Cord InjuryNeurosurgery, 2002
- Why Do You Prescribe Methylprednisolone for Acute Spinal Cord Injury? A Canadian Perspective and a Position StatementCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2002
- The Role of Steroids in Acute Spinal Cord InjurySpine, 2001
- Questionnaire Survey of the Views of the Delegates at the European Cervical Spine Research Society Meeting on the Administration of Methylprednisolone for Acute Traumatic Spinal Cord InjurySpine, 2001
- Is the role of steroids in acute spinal cord injury now resolved?Current Opinion in Neurology, 2001
- A Critical Appraisal of the Reporting of the National Acute Spinal Cord Injury Studies (II and III) of Methylprednisolone in Acute Spinal Cord InjuryJournal of Spinal Disorders, 2000
- Corticosteroids in acute spinal cord injuryEmergency Medicine Journal, 2000
- Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study.1997