Endothelial Decompensation in a Schizophrenic Patient Receiving Long-Term Treatment with Tranquilizers

Authors:
  • YOYuichi Ohashi
    Yuichi Ohashi
  • SKShigeru Kinoshita
    Shigeru Kinoshita
  • AKAkira Kiritoshi
    Akira Kiritoshi
  • RMReizo Manabe
    Reizo Manabe
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Abstract
Bilateral corneal edema occurred in a schizophrenic patient receiving tranquilizers. This particular corneal edema was rapidly resolved after tranquilizer discontinuation. Specular microscopic examination disclosed marked enlargement of the corneal endothelium. This endothelial impairment may have been due to long-term administration of tranquilizers.