Oleanolic acid inhibits M2 macrophage polarization and potentiates anti-PD-1 therapy in hepatocellular carcinoma by targeting miR-130b-3p-PTEN-PI3K-Akt signaling and glycolysis
- 9 April 2025
- journal article
- Published by Elsevier in Phytomedicine
- Vol. 141, 156750
Abstract
No abstract availableKeywords
Funding Information
- Shanghai Municipal Education Commission
- National Natural Science Foundation of China (82074203, 82374540, 82274328)
This publication has 45 references indexed in Scilit:
- The GLOBOCAN 2022 cancer estimates: Data sources, methods, and a snapshot of the cancer burden worldwideInternational Journal of Cancer, 2024
- Drug-resistant exosome miR-99b-3p induces macrophage polarization and confers chemoresistance on sensitive cells by targeting PPP2CAInternational Immunopharmacology, 2024
- Therapeutic potential of oleanolic acid in liver diseasesNaunyn-Schmiedeberg's Archives of Pharmacology, 2024
- Colorectal cancer tumor cell-derived exosomal miR-203a-3p promotes CRC metastasis by targeting PTEN-induced macrophage polarizationGene, 2023
- CircDENND2D Inhibits PD-L1-Mediated Non-Small Cell Lung Cancer Metastasis and Immune Escape by Regulating miR-130b-3p/STK11 AxisBiochemical Genetics, 2023
- Hypoxia signaling in hepatocellular carcinoma: Challenges and therapeutic opportunitiesCancer and Metastasis Reviews, 2022
- Updated efficacy and safety data from IMbrave150: Atezolizumab plus bevacizumab vs. sorafenib for unresectable hepatocellular carcinomaJournal of Hepatology, 2022
- Construction of TME and Identification of crosstalk between malignant cells and macrophages by SPP1 in hepatocellular carcinomaCancer Immunology, Immunotherapy, 2021
- Cytotoxicity of oleanolic and ursolic acid derivatives toward hepatocellular carcinoma and evaluation of NF-κB involvementBioorganic Chemistry, 2019
- miR-130b-3p inhibits cell invasion and migration by targeting the Notch ligand Delta-like 1 in breast carcinomaGene, 2017