The opportunities and effectiveness of the use of autologous platelet-rich plasma in plastic surgery, anti-age medicine and dermatology

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Abstract
Today, the use of autologous platelet-rich plasma expands the horizons of its use in medicine. However, to uncover the key factors of plasma effectiveness, more data is required, describing in detail the method of plasma preparation, the amount of material introduced, as well as data on a comparative analysis of various methods of its administration. The purpose of this review was to search for data on the use of autologous plasma in the fields of Anti-Age medicine, plastic surgery and dermatology with a description of the methodology, as well as local and general effects. Publications of foreign and domestic authors in the Scopus and Pubmed databases were analyzed. When searching using the keywords: platelet rich plasma, safety, effects, dermatology, cosmetology, surgery, melasma, acne, 570 publications were found. Taking into account the depth of the search (the last 5 years), the language of publications (Russian, English), 32 full-text articles were included in the analysis. The presence of a large number of studies demonstrates the high interest of scientists from all over the world in studying the properties and effectiveness of plasma. Positive results of using plasma were presented in the field of plastic surgery, cosmetology, and dermatology. However, the lack of a detailed description of the methodology of the procedure, and moreover, a unified standard algorithm for the procedure and criteria for admission to receiving plasma, creates difficulty in comparability of results, both positive and negative. Therefore, additional larger studies are required to help answer these unresolved questions.

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