Investigating the Impact of Food Induced Fluid Viscosity on Disintegration and Dissolution of Immediate Release Midodrine HCl Tablet
Authors:
- Fathima T. DooleFDFathima T. Doole
- Ranganath Wahalathantrige DonRDRanganath Wahalathantrige Don
- Ishwor PoudelIshwor Poudel
- Timothy LexTLTimothy Lex
- Yi-Hsien ChengYi-Hsien Cheng
- Fang WuFang Wu
- Wei-Jhe SunWei-Jhe Sun
- Lei ZhangLei Zhang
- Peter LangguthPeter Langguth
- Wenlei JiangWenlei Jiang
- Zongming GaoZongming Gao
- 8 September 2026
- journal article
- Published by Springer Nature in The AAPS Journal
- Vol. 28 (5) , 136
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Development of Sustained Release System Based on High Water-Absorbable Gel Formation Using Croscarmellose Sodium, Alkaline Excipients and HPMC (ACSH SR System); Novel Application of Croscarmellose Sodium as a Gel FormerPharmaceutical Research, 2023
- Effect of Food Viscosity on Drug DissolutionPharmaceutical Research, 2023
- Solid Dosage Forms2023
- In vitro investigation of the effect of food texture, particle size, and viscosity on gastric disintegration and emptyingFood Bioengineering, 2022
- A Comparison of EMA and FDA Decisions for New Drug Marketing Applications 2014–2016: Concordance, Discordance, and WhyClinical Pharmacology & Therapeutics, 2019
- A Review of Disintegration Mechanisms and Measurement TechniquesPharmaceutical Research, 2017
- Mechanistic investigation of food effect on disintegration and dissolution of BCS class III compound solid formulations: the importance of viscosityBiopharmaceutics & Drug Disposition, 2012
- Dissolution Media Simulating Conditions in the Proximal Human Gastrointestinal Tract: An UpdatePharmaceutical Research, 2008
- Immediate Drug Release from Solid Oral Dosage FormsJournal of Pharmaceutical Sciences, 2005
- A Preliminary Report of the Effect of Gastric Mucous upon Tablet Disintegration**LaWall and Harrisson Research Laboratories, Philadelphia, Pa.Journal of the American Pharmaceutical Association (Scientific ed.), 1959