Hypertensive Heart Disease and Obesity: A Complex Interaction Between Hemodynamic and Not Hemodynamic Factors
- 13 May 2014
- journal article
- review article
- Published by Springer Nature in High Blood Pressure & Cardiovascular Prevention
- Vol. 21 (2) , 81-87
Abstract
The worldwide prevalence of obesity has nearly doubled, with an increase in obesity-related cardiovascular disease and mortality. Several factors are involved in the genesis of hypertension and hypertensive heart disease (HHD) in overweight/obesity. This review is focused on bridging factors between excessive adiposity and HHD, presenting a unifying hypothesis of vascular–metabolic syndrome, where an “handicap” of the natriuretic peptide system has a central role both in adipocyte dysmetabolism as well as in increased blood pressure and HHD.Keywords
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