Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population
- 1 February 1991
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 86 (4) , 369-370
Abstract
We describe a simple method for characterizing a frequent polymorphism (that subsitutes an arginine for a proline) in the coding sequence of the Tp53 gene in patients with colonic cancer and in a control population. We could find no evidence that this polymorphism is associated with a marked predisposition to colorectal cancer.Keywords
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