Urinary proteomics: fancy gadgetry or a clinically useful diagnostic instrument? The end-user's perspective

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Abstract
Late deterioration of kidney function is a major challenge in transplantation medicine, thus early detection of subclinical kidney damage is of outstanding importance. Conventional laboratory parameters such as declining kidney function assessed by serum creatinine or creatinine clearance and proteinuria are late indicators of an already established damage. While urine properties have long been the subject of medical investigations, classical parameters based on physico‐chemical properties and microscopic analysis remain far from helpful for establishing a refined etiological diagnosis and generally do not indicate the stage of kidney disease.
Funding Information
  • Hungarian National Research, Development and Innovation Office (NKFI-124549)

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