Agglutinin Response to Pertussis Vaccination in the Child

Authors:
  • JAJ. D. Abbott
    J. D. Abbott
  • NPN. W. Preston
    N. W. Preston
  • RMR. I. Mackay
    R. I. Mackay
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Abstract
Children were immunized with plain pertussis vaccine made by three manufacturers in 1967. After a primary course of three injections at monthly intervals, starting at 3-4 months of age, the agglutinin response was poor. Even after a “booster” dose, given five months later, not all of the vaccines had stimulated a response to all three pertussis agglutinogens. A further investigation with current vaccines of different kinds administered according to more than one schedule is recommended.