Highlighting vulnerabilities in the alternative lengthening of telomeres pathway
Authors:
- 5 May 2023
- journal article
- research article
- Published by Elsevier in Current Opinion in Pharmacology
- Vol. 70, 102380
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health
- National Cancer Institute (R01CA201446, R01CA214880)
This publication has 63 references indexed in Scilit:
- Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cellsJournal of Cell Biology, 2012
- Human telomeres replicate using chromosome-specific, rather than universal, replication programsJournal of Cell Biology, 2012
- Prevalence of the Alternative Lengthening of Telomeres Telomere Maintenance Mechanism in Human Cancer SubtypesThe American Journal of Pathology, 2011
- Altered Telomeres in Tumors with ATRX and DAXX MutationsScience, 2011
- Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeresProceedings of the National Academy of Sciences, 2010
- Alternative lengthening of telomeres: models, mechanisms and implicationsNature Reviews Genetics, 2010
- Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic RegionsCell, 2010
- DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activityNature Biotechnology, 2009
- The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forksGenes & Development, 2009
- Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient ReplicationCell, 2009