Sponge‐like chitosan‐based nanostructured antibacterial material as a topical hemostat
- 11 January 2019
- journal article
- research article
- Published by Wiley in Journal of Applied Polymer Science
- Vol. 136 (19)
Abstract
In this study, chitosan/alginic acid/zinc oxide (CHI/AA/ZnO) nanostructured hydrogel sponges were fabricated by incorporating ZnO nanoparticles (Staphylococcus aureus. The cytotoxicity and hemostatic efficacy of crosslinked CHI/AA/ZnO sponge like‐nanostructured hydrogels was evaluated in vitro and in vivo, respectively. The results of this study demonstrated that the prepared CHI/AA/ZnO nanostructured sponge had the potential to be an antibacterial topical hemostat. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47522.Keywords
Funding Information
- TUBITAK MRC (5143401)
This publication has 48 references indexed in Scilit:
- Genipin-Crosslinked Cartilage-Derived Matrix as a Scaffold for Human Adipose-Derived Stem Cell ChondrogenesisTissue Engineering Part A, 2013
- Modified chitosan hydrogels as drug delivery and tissue engineering systems: present status and applicationsActa Pharmaceutica Sinica B, 2012
- Cytotoxicity and biocompatibility evaluation of N,O-carboxymethyl chitosan/oxidized alginate hydrogel for drug delivery applicationInternational Journal of Biological Macromolecules, 2012
- Flexible and Microporous Chitosan Hydrogel/Nano ZnO Composite Bandages for Wound Dressing: In Vitro and In Vivo EvaluationACS Applied Materials & Interfaces, 2012
- Oxidized regenerated cellulose-based hemostat with microscopically gradient structureCarbohydrate Polymers, 2012
- Effects of different cross-linking conditions on the properties of genipin-cross-linked chitosan/collagen scaffolds for cartilage tissue engineeringJournal of Materials Science: Materials in Medicine, 2010
- Degradable, antibacterial silver exchanged mesoporous silica spheres for hemorrhage controlBiomaterials, 2009
- A review of the antimicrobial activity of chitosanPolímeros, 2009
- Antibacterial activity of N-alkylated disaccharide chitosan derivativesInternational Journal of Food Microbiology, 2005
- Drug release from chitosan–alginate complex beads reinforced by a naturally occurring cross-linking agentCarbohydrate Polymers, 2002