Salivary Biomarkers in Periodontitis: A Scoping Review
Authors:
Open Access
- 8 December 2023
- journal article
- review article
- Published by Springer Nature in Cureus
- Vol. 15 (12) , e50207
Abstract
Periodontal disease is a prevalent and potentially impactful oral health condition, ranging from gingivitis to severe periodontitis. Early detection and precise management are crucial in modern dentistry due to its prevalence and potential systemic health implications. Traditional clinical assessments and radiographic imaging have been the primary diagnostic tools. However, recent advances in oral diagnostics have introduced the concept of non-invasive, easily accessible salivary biomarkers. This review explores the evolving landscape of salivary biomarkers associated with periodontal disease, offering a comprehensive analysis of recent studies. It delves into the key findings, clinical significance, and potential impact of these biomarkers in revolutionizing periodontal disease diagnostics and treatment monitoring. The study emphasizes their diagnostic and prognostic capabilities, including their ability to assess disease severity, correlate with clinical parameters, aid in early detection, and enhance personalized treatment planning. As the field of oral diagnostics continues to advance, understanding the role of salivary biomarkers in periodontal disease management holds the promise of improving precision and effectiveness in oral healthcare. This review underscores the potential for salivary biomarkers to become integral components of routine periodontal care, offering a minimally invasive and patient-centered approach to oral health management.Keywords
This publication has 30 references indexed in Scilit:
- Study Design Considerations for Cancer Biomarker DiscoveriesThe Journal of Applied Laboratory Medicine, 2018
- A new classification scheme for periodontal and peri‐implant diseases and conditions – Introduction and key changes from the 1999 classificationJournal of Clinical Periodontology, 2018
- A quantitative point-of-care test for periodontal and dental peri-implant diseasesNature Reviews Disease Primers, 2017
- Salivary cytokines as biomarkers of periodontal diseasesPeriodontology 2000, 2015
- Targeted salivary biomarkers for discrimination of periodontal health and disease(s)Frontiers in Cellular and Infection Microbiology, 2015
- Salivary Biomarkers Associated With Gingivitis and Response to TherapyJournal of Periodontology, 2014
- Periodontal Treatment Reduces Matrix Metalloproteinase Levels in Localized Aggressive PeriodontitisJournal of Periodontology, 2013
- Salivary Biomarkers in the Diagnosis of Periodontal DiseaseJournal of the California Dental Association, 2013
- Bacterial and Salivary Biomarkers Predict the Gingival Inflammatory ProfileJournal of Periodontology, 2012
- Saliva: A diagnostic biomarker of periodontal diseasesJournal of Indian Society of Periodontology, 2011