Guidelines for Trypanosoma cruzi-HIV Co-infection and other Immunosuppressive Conditions: Diagnosis, Treatment, Monitoring, and Implementation from the International Network of Care and Studies - 2023

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Abstract
Since the Brazilian Ministry of Health’s 1992 revision to the case definition of acquired immunodeficiency syndrome (AIDS), there has been scientific evidence showing that certain endemic infectious and parasitic processes, such as Chagas disease, visceral leishmaniasis, and paracoccidioidomycosis, can induce opportunistic behaviour in individuals with advanced Human Immunodeficiency Virus (HIV). This situation requires distinct clinical protocols within the healthcare network and epidemiological surveillance measures. These actions aim to incorporate clinical events as indications of AIDS.

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