Diffusion-weighted imaging in the evaluation of odontogenic cysts and tumours

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Abstract
Objective The differentiation between keratocystic odontogenic tumour (KCOT) and other cystic/predominantly cystic odontogenic tumours is difficult on conventional CT and MR sequences as there is overlap in the imaging characteristics of these lesions. The purpose of this study was to evaluate the role of diffusion-weighted imaging (DWI) and to assess the performance of apparent diffusion coefficients (ADCs) in the differential diagnosis of odontogenic cysts and tumours. Methods 20 patients with odontogenic cysts and tumours of the maxillomandibular region were examined with DWI. Diffusion-weighted images were obtained with a single-shot echoplanar technique with b-values of 0, 500 and 1000 s mm−2. An ADC map was obtained at each slice position. Results The cystic areas of ameloblastoma (n=10) showed free diffusion with a mean ADC value of 2.192±0.33×10−3 mm2 s−1, whereas the solid areas showed restricted diffusion with a mean ADC value of 1.041±0.41×10−3 mm2 s−1. KCOT (n=5) showed restricted diffusion wi...

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