EFFECTS OF ETHOXYQUIN ON AFLATOXIN–PRODUCING STRAINS OF Aspergillus parasiticus AND A. flavus

Authors:
  • JAJ. C. Ayres
    J. C. Ayres
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Abstract
Seven isolates of A. parasiticus and A. flavus were grown for 10 days on a semi‐synthetic medium containing 25–150 ppm ethoxquin antioxidant. In isolates producing B and G toxins, aflatoxin B levels increased 5–12 times over that of controls while G toxins decreased 32–97%. The increase in B toxins was not concentration‐dependent, but the decrease in G toxins was. In isolates of A. flavus and A. parasiticus producing only B toxins, aflatoxin levels were depressed or remained unchanged. The effect of 100 ppm ethoxyquin on 15 isolates of A. parasiticus and A. flavus , including some altered in aflatoxin‐producing capability by mutation, was examined. Among wild‐type isolates of A. parasiticus G 1 decreased 90% and G 2 , was completely inhibited; B 1 increased 67–1100% and B 2 increased 100–300%. Toxin synthesis was decreased 66–95% among wild‐types and mutants of A. flavus and A. parasiticus producing only B toxins. Ethoxquin apparently had little or no effect on mutants which consistently produce very low levels of the aflatoxins. The results indicate that the use of ethoxyquin as a feed additive may aggravate potential mycotoxin hazards in contaminated feedstuffs.

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