Interexpert Agreement in the Identification of Macular Location in Infants at Risk for Retinopathy of Prematurity

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Abstract
Retinopathy of prematurity (ROP) is a vasoproliferative disease affecting low-birth-weight infants and is a leading cause of childhood blindness worldwide. Major advances in diagnosis and treatment have occurred. For example, the International Classification of ROP established a standard system for describing examination findings, thereby creating a foundation for clinical care and research.1,2 The Cryotherapy for ROP3 (CRYO-ROP) and Early Treatment for ROP4 (ETROP) trials identified criteria for which treatment with cryotherapy or laser photocoagulation was shown to improve visual outcomes.

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