One-Step Photoreduction of Nitroarenes to Nitrosoarenes

Authors:
Open Access
Publisher website
Google Scholar
Abstract
Nitrosoarenes are versatile synthons, but their selective synthesis from abundant feedstocks remains challenging because conventional methods often require harsh conditions that can result in over-reduction and over-oxidation. Here, we report a photomediated deoxygenation of nitroarenes to nitrosoarenes using electron-poor phosphines as oxygen atom acceptors. Careful selection of the oxygen atom acceptor enables selective arrest at the nitroso oxidation state, affording nitrosoarenes directly from nitroarenes in good yields under mild conditions.
Funding Information
  • NIH Office of the Director (S10OD028488)
  • Wayne State University
  • National Institute of General Medical Sciences (R01GM098285- 07S1)
  • National Science Foundation (0840413)
  • National Science Foundation (2303622)

This publication has 62 references indexed in Scilit: