Histamine Release in vitro: Inhibition by Catecholamines and Methylxanthines
Authors:
- 30 August 1968
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 161 (3844) , 902-903
Abstract
Methylxanthines and catecholamines both inhibit antigenically induced histamine release from human leukocytes. They act synergistically to inhibit the reaction, but must be present when antigen is added; preincubation is not effective. Since both increase cellular levels of cyclic 3′,5′-adenosine monophosphate it is postulated that this compound plays a role in the regulation of allergic histamine release.Keywords
This publication has 7 references indexed in Scilit:
- Insulin Release After ACTH, Glucagon and Adenosine-3′-5′-Phosphate (Cyclic AMP) in the Perfused Isolated Rat PancreasDiabetes, 1967
- In vitro assay of allergenic properties of ragweed pollen antigensJournal of Allergy, 1966
- In Vitro Studies of Human Ragweed Allergy: Changes in Cellular and Humoral Activity Associated with Specific Desensitization*Journal of Clinical Investigation, 1966
- STUDIES ON THE MECHANISMS OF HYPERSENSITIVITY PHENOMENAJournal of Experimental Medicine, 1964
- Studies on UDPG-α-glucan Transglucosylase. V. Two Forms of the Enzyme in Dog Skeletal Muscle and Their Interconversion*Biochemistry, 1964
- Adenosine 3‘,5‘-Phosphate in Biological MaterialsJournal of Biological Chemistry, 1962
- Adenyl CyclaseJournal of Biological Chemistry, 1962