Non-fibrillar Components of Amyloid Deposits Mediate the Self-association and Tangling of Amyloid Fibrils
Authors:
- Christopher A. MacRaildCMChristopher A. MacRaild
- Cameron R. StewartCSCameron R. Stewart
- Yee-Foong MokYMYee-Foong Mok
- Menachem J. GunzburgMGMenachem J. Gunzburg
- Matthew A. PeruginiMPMatthew A. Perugini
- Lynne J. LawrenceLLLynne J. Lawrence
- Viyada TirtaatmadjaVTViyada Tirtaatmadja
- Justin J. Cooper-WhiteJCJustin J. Cooper-White
- Geoffrey J. HowlettGHGeoffrey J. Howlett
Open Access
- 1 May 2004
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 279 (20) , 21038-21045
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- Sedimentation Velocity Analysis of Flexible Macromolecules: Self-Association and Tangling of Amyloid FibrilsBiophysical Journal, 2003
- Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosisNature, 2002
- Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseasesNature, 2002
- Deposition of Transthyretin in Early Stages of Familial Amyloidotic PolyneuropathyThe American Journal of Pathology, 2001
- Pathogenesis, diagnosis and treatment of systemic amyloidosisPhilosophical Transactions of the Royal Society B: Biological Sciences, 2001
- Islet Amyloid and Type 2 Diabetes MellitusNew England Journal of Medicine, 2000
- Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapyProceedings of the National Academy of Sciences, 2000
- Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxinsProceedings of the National Academy of Sciences, 1998
- From the globular to the fibrous state: protein structure and structural conversion in amyloid formationQuarterly Reviews of Biophysics, 1998
- Amyloid plaque core protein in Alzheimer disease and Down syndrome.Proceedings of the National Academy of Sciences, 1985