Receptor-Dependent Coronavirus Infection of Dendritic Cells
Open Access
- 15 May 2004
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 78 (10) , 5486-5490
Abstract
In several mammalian species, including humans, coronavirus infection can modulate the host immune response. We show a potential role of dendritic cells (DC) in murine coronavirus-induced immune modulation and pathogenesis by demonstrating that the JAW SII DC line and primary DC from BALB/c mice and p/p mice with reduced expression of the murine coronavirus receptor, murine CEACAM1a, are susceptible to murine coronavirus infection by a receptor-dependent pathway.Keywords
This publication has 47 references indexed in Scilit:
- The Genome Sequence of the SARS-Associated CoronavirusScience, 2003
- Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory SyndromeScience, 2003
- Varicella-Zoster Virus Productively Infects Mature Dendritic Cells and Alters Their Immune FunctionJournal of Virology, 2003
- DC-SIGN (CD209) Mediates Dengue Virus Infection of Human Dendritic CellsJournal of Experimental Medicine, 2003
- Targeted Disruption of theCeacam1(MHVR) Gene Leads to Reduced Susceptibility of Mice to Mouse Hepatitis Virus InfectionJournal of Virology, 2001
- Varicella-Zoster Virus Infection of Human Dendritic Cells and Transmission to T Cells: Implications for Virus Dissemination in the HostJournal of Virology, 2001
- B lymphocyte and macrophage expression of carcinoembryonic antigen‐related adhesion molecules that serve as receptors for murine coronavirusEuropean Journal of Immunology, 1994
- A review of feline infectious peritonitis virus: molecular biology, immunopathogenesis, clinical aspects, and vaccinationVeterinary Microbiology, 1993
- Human aminopeptidase N is a receptor for human coronavirus 229ENature, 1992
- Aminopeptidase N is a major receptor for the enteropathogenic coronavirus TGEVNature, 1992