Controlling Long-Term Signaling: Receptor Dynamics Determine Attenuation and Refractory Behavior of the TGF-β Pathway
- 10 December 2013
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Signaling
- Vol. 6 (305) , ra106
Abstract
Ligand binding, but not receptor activity, results in desensitization and long-term dampening of cellular responsiveness to TGF-β.Keywords
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