Prognostic Risk Factors in Randomized Clinical Trials of Face-to-Face and Internet-Based Psychotherapy for Depression

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Abstract
Psychotherapy for depression can be offered in different settings and treatment modalities. Traditionally, treatment is delivered face to face, but internet-based therapy (IBT) has gained popularity and the number of randomized clinical trials (RCTs) of IBT has grown during the past 2 decades.1 Recent direct and indirect comparisons2,3 suggest that therapist-guided IBT can be as beneficial as face-to-face therapy (FTF).

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