Predictors of toxic metal exposures among US women of reproductive age
Authors:
- 24 June 2019
- journal article
- research article
- Published by Springer Nature in Journal of Exposure Science & Environmental Epidemiology
- Vol. 29 (5) , 597-612
Abstract
Background Arsenic, cadmium, lead, and mercury are ubiquitous toxicants that may be especially harmful to unborn children. We therefore sought to identify temporal trends and predictors of toxic metal biomarkers among US women of reproductive age, including those who were pregnant and/or breastfeeding. Methods Interviews and examinations were performed among a representative sample of women, aged 20–44 years, as part of the 2003–2014 National Health and Nutrition Examination Surveys. A range of sociodemographic, lifestyle, and dietary factors were evaluated as predictors of urinary inorganic arsenic, urinary cadmium, blood mercury, and blood lead concentrations. Results Levels of all four toxic metal biomarkers declined during the study period. Older age, racial/ethnic minorities, and a birthplace outside of the US were independently associated with higher toxic metal concentrations. Associations were similar for women who were pregnant or breastfeeding and those who were not. Conclusion US women of reproductive age were exposed to lower levels of toxic metals in 2013–2014 compared to 2003–2004. However, because the long-term health effects of early life exposures are unclear, public health efforts to address toxic metals should pay particular attention to older, nonwhite, and foreign-born women if they are pregnant or planning to become pregnant.Keywords
This publication has 43 references indexed in Scilit:
- Mercury, lead and cadmium in human milk in relation to diet, lifestyle habits and sociodemographic variables in Madrid (Spain)Chemosphere, 2011
- Probability of intellectual disability is associated with soil concentrations of arsenic and leadChemosphere, 2011
- Probabilistic Modeling of Dietary Arsenic Exposure and Dose and Evaluation with 2003–2004 NHANES DataEnvironmental Health Perspectives, 2010
- The placenta as a barrier for toxic and essential elements in paired maternal and cord blood samples of South African delivering womenJournal of Environmental Monitoring, 2009
- Biological half-life of cadmium in the urine of inhabitants after cessation of cadmium exposureBiomarkers, 2009
- Association between the plasma/whole blood lead ratio and history of spontaneous abortion: a nested cross-sectional studyBMC Pregnancy and Childbirth, 2007
- Dose–Response Relationship of Prenatal Mercury Exposure and IQ: An Integrative Analysis of Epidemiologic DataEnvironmental Health Perspectives, 2007
- Urinary Creatinine Concentrations in the U.S. Population: Implications for Urinary Biologic Monitoring MeasurementsEnvironmental Health Perspectives, 2005
- Exposure of the U.S. population to lead, 1991-1994.Environmental Health Perspectives, 1998
- Effects of low-level lead exposure on 24 h activity patterns in the mouseToxicology Letters, 1988