Natural Human Antibodies to Gram-Negative Bacteria: Immunoglobulins G, A, and M
Authors:
- 27 May 1966
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 152 (3726) , 1257-1259
Abstract
Significant amounts of immunoglobulins G and M, and a small amount of natural antibodies reactive with Neisseria gonorrhoeae and Escherichia coli , have been detected in human adult serums by immunofluorescent techniques. Umbilical cord serums also contained substantial immunoglobulin-G antibody but little or no M or A. These findings challenge the concept that natural antibodies reactive with Gram-negative bacteria are primarily of the immunoglobulin-M class.Keywords
This publication has 14 references indexed in Scilit:
- Complement Fixation on Cell Surfaces by 19 S and 7 S AntibodiesScience, 1965
- THE ISOLATION AND BIOLOGICAL ACTIVITIES OF RABBIT γM- AND γG-ANTI-SALMONELLA TYPHIMURIUM ANTIBODIESJournal of Experimental Medicine, 1965
- SINGLE CELL STUDIES ON 19S ANTIBODY PRODUCTIONJournal of Experimental Medicine, 1964
- ASSOCIATION OF "NATURAL" ANTIBODIES TO GRAM-NEGATIVE BACTERIA WITH THE γ1-MACROGLOBULINSJournal of Experimental Medicine, 1963
- SEQUENCES OF SYNTHESIS OF γ-1 MACROGLOBULIN AND γ-2 GLOBULIN ANTIBODIES DURING PRIMARY AND SECONDARY RESPONSES TO PROTEINS, SALMONELLA ANTIGENS, AND PHAGEJournal of Experimental Medicine, 1963
- ANTIBODY FORMATIONJournal of Experimental Medicine, 1963
- Fractionation of human-serum proteins by gel filtrationBiochimica et Biophysica Acta, 1962
- THE FORMATION OF MACROGLOBULIN ANTIBODIES. I. STUDIES ON ADULT HUMANS*Journal of Clinical Investigation, 1962
- STUDIES ON NATURAL ANTIBODIES TO GRAM-NEGATIVE BACTERIAJournal of Experimental Medicine, 1962
- Immunity in InfancyPediatric Clinics of North America, 1960