Association of naturally occurring antibodies to β-amyloid with cognitive decline and cerebral amyloidosis in Alzheimer’s disease
Open Access
- 1 January 2021
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Advances
- Vol. 7 (1) , eabb0457
Abstract
NAbs to different epitopes of Aβ are differentially associated with the severity and progression of Alzheimer’s disease.Keywords
Funding Information
- National Natural Science Foundation of China (91749206)
- National Natural Science Foundation of China (81625007)
- National Natural Science Foundation of China (81671277)
- National Natural Science Foundation of China (81600936)
- Chinese Ministry of Science and Technology (2016YFC1306401)
This publication has 37 references indexed in Scilit:
- NEWS FROM THE ALZHEIMER'S ASSOCIATION INTERNATIONAL CONFERENCENeurology Today, 2013
- Autoreactive‐Aβ antibodies promote APP β‐secretase processingJournal of Neurochemistry, 2011
- Vascular risk factors promote conversion from mild cognitive impairment to Alzheimer diseaseNeurology, 2011
- The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's diseaseInternational Psychogeriatrics, 2009
- Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's diseaseProceedings of the National Academy of Sciences, 2009
- Differential neuroimmune markers to the onset of Alzheimer's disease neurodegeneration and dementia: Autoantibodies to Aβ(25–35) oligomers, S100b and neurotransmittersJournal of Neuroimmunology, 2007
- Immunology and immunotherapy of Alzheimer's diseaseNature Reviews Immunology, 2006
- Decreased serum amyloid β1–42 autoantibody levels in Alzheimer’s disease, determined by a newly developed immuno-precipitation assay with radiolabeled amyloid β1–42 peptideBiological Psychiatry, 2005
- Autoantibodies to Amyloid β-Peptide (Aβ) are Increased in Alzheimer's Disease Patients and Aβ Antibodies Can Enhance Aβ Neurotoxicity: Implications for Disease Pathogenesis and Vaccine DevelopmentNeuroMolecular Medicine, 2003
- A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMRProceedings of the National Academy of Sciences, 2002