Different thresholds of tissue-specific dose-responses to growth hormone in short prepubertal children
Open Access
- 1 November 2012
- journal article
- research article
- Published by Springer Nature in BMC Endocrine Disorders
- Vol. 12 (1) , 26
Abstract
In addition to stimulating linear growth in children, growth hormone (GH) influences metabolism and body composition. These effects should be considered when individualizing GH treatment as dose-dependent changes in metabolic markers have been reported. Hypothesis : There are different dose-dependent thresholds for metabolic effects in response to GH treatment.Keywords
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