Supplementary Figure S2 from PRMT5 Inhibition by SCR-6920 Downregulates HIF-1α and Exhibits Synergistic Antitumor Activity with Bevacizumab in Ovarian Cancer

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Abstract
Supplementary Figure S2 shows per-residue energy decomposition for SCR-6920 and GSK3235025 bound to PRMT5, comparing van der Waals, non-polar solvation, electrostatic, and total interaction energies across the binding pocket residues.