Multiple Myeloma Lesion Detection With Whole Body CT Versus Radiographic Skeletal Survey
Authors:
- Michael MulliganMMMichael Mulligan
- 13 February 2013
- journal article
- research article
- Published by Taylor & Francis in Cancer Investigation
- Vol. 31 (3) , 206-211
Abstract
Objective: To compare accuracy of CT versus radiographs in detecting myeloma lesions. Materials and Methods: Retrospective review of patients who were simultaneously evaluated with radiographs and PET/CT scans. Two radiologists independently assessed each modality. Results: Total number of lesions detected with CT was 968 versus 248 for radiographs (p < .001). Nine patients (18%) had no lesions on either CT or radiographs. Of the remaining 42 patients, 39 had more lesions on CT. CT could have resulted in upstaging of disease in 31 cases (61%). Conclusion: CT is superior for detecting myeloma lesions.Keywords
This publication has 18 references indexed in Scilit:
- Cancer statistics, 2011CA: A Cancer Journal for Clinicians, 2011
- Prognostic Significance of Focal Lesions in Whole-Body Magnetic Resonance Imaging in Patients With Asymptomatic Multiple MyelomaJournal of Clinical Oncology, 2010
- International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple MyelomaLeukemia, 2009
- Magnetic Resonance Imaging in Multiple Myeloma: Diagnostic and Clinical ImplicationsJournal of Clinical Oncology, 2007
- The benefit of using whole‐body, low‐dose, nonenhanced, multidetector computed tomography for follow‐up and therapy response monitoring in patients with multiple myelomaCancer, 2007
- The role of anatomic and functional staging in myeloma: Description of Durie/Salmon plus staging systemEuropean Journal of Cancer, 2006
- Role of MRI for the diagnosis and prognosis of multiple myelomaEuropean Journal of Radiology, 2005
- Myeloma management guidelines: a consensus report from the Scientific Advisors of the International Myeloma FoundationThe Hematology Journal, 2003
- Magnetic resonance imaging as a supplement for the clinical staging system of Durie and Salmon?Cancer, 2002
- Risk of disease progression in asymptomatic multiple myelomaThe American Journal of Medicine, 1993