What day is today? Cognitive capacity and the risk of incident dementia in the context of integrated care for older people (ICOPE Step 1)

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Abstract
Based on clinical observations, our objective was to test if the older adults who failed to recall the name of the weekday, or had a higher number of mistakes in the word recall were at higher risk of mild cognitive impairment (MCI) or dementia. Longitudinal data of the Multidomain Alzheimer Preventive Trial (MAPT) was used to retrospectively measure the cognitive capacity according to the ICOPE Step 1 tool. Incident dementia was assessed by two multidisciplinary committees independent from each other. MCI was defined as Clinical Dementia Rating scale CDR = 0.5. Failure to recall the name of the weekday had a three-fold risk of incident dementia in the next 5 years (HRa = 3.11, 95%CI: 1.18–8.17). Having two or three mistakes in the word recall carried a higher risk of incident dementia, (HRa for two mistakes = 3.50, 95% CI: 1.49–8.26; HRa for three mistakes = 4.28, 95% CI: 1.60–11.46), but not MCI. People with impaired cognitive capacity according to the ICOPE Step 1 tool deserve further assessment and a closer follow-up.
Funding Information
  • European Regional Development Fund (MP0022856)
  • Region Occitanie/Pyrénées-Méditerranée (Reference number: 1901175)
  • Ministère des Affaires Sociales, de la Santé et des Droits des Femmes (PHRC 2008, 2009)

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