The role of copper and the copper-related protein CUTA in mediating APP processing and Aβ generation
- 1 March 2015
- journal article
- Published by Elsevier in Neurobiology of Aging
- Vol. 36 (3) , 1310-1315
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (81225008, 81161120496, 91332112, 91332114)
- Fundamental Research Funds (2012121048)
This publication has 28 references indexed in Scilit:
- Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activationMolecular Neurodegeneration, 2013
- Copper and Oxidative Stress in the Pathogenesis of Alzheimer’s DiseaseBiochemistry, 2012
- BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s diseaseMolecular Neurodegeneration, 2012
- Gene expression profiling in chronic copper overload reveals upregulation ofPrnpandAppPhysiological Genomics, 2004
- Copper Depletion Down-regulates Expression of the Alzheimer's Disease Amyloid-β Precursor Protein GeneJournal of Biological Chemistry, 2004
- Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic miceProceedings of the National Academy of Sciences, 2003
- The Evolutionarily Conserved Trimeric Structure of CutA1 Proteins Suggests a Role in Signal TransductionJournal of Biological Chemistry, 2003
- Copper, Zinc, and the Metallobiology of Alzheimer DiseaseAlzheimer Disease & Associated Disorders, 2003
- Copper inhibits β-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretionBiochemical Journal, 1999
- Molecular genetics of a chromosomal locus involved in copper tolerance in Escherichia coli K‐12Molecular Microbiology, 1995