Attenuation of Choroidal Neovascularization by β2-Adrenoreceptor Antagonism

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Abstract
Exudative age-related macular degeneration (AMD) is one of the leading causes of blindness worldwide.1 Exudative AMD develops when vascular tissue from the choriocapillaris invades through a break in the Bruch membrane into the subretinal pigment epithelium and/or subretinal space; this process is termed choroidal neovascularization (CNV). Leakage of blood, serous fluid, and lipid due to CNV causes central vision loss and ultimately leads to an irreversible fibrovascular scar.1

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