Clinical trial of patulin in the common cold

Author:
  • PCPatulin Clinical Trials Committee, Medical Research Council
    Patulin Clinical Trials Committee, Medical Research Council
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Abstract
In November, 1943, a report was published of the chemical properties and clinical effects of a metabolic product of Penicillium patulum Bainier, called patulin.1 It was shown in a clinical trial on the common cold in naval personnel that when 95 patients treated with patulin were compared with 85 controls, the advantage to the treated patients was such that it would usually be regarded as statistically significant. The results obtained were considered encouraging, but no definite claims were made.