Characterization of the Hanganutziu-Deicher (Serum-Sickness) Antigen as Gangliosides Containing N-Glycolylneuraminic Acid
Authors:
- J.M. MerrickJMJ.M. Merrick
- K. ZadarlikKZK. Zadarlik
- F. MilgromFMF. Milgrom
- 1 January 1978
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 57 (5) , 477-480
Abstract
Gangliosides that possess the same sugar sequence but differing in the type of sialic acid (N-acetyl- or N-glycolylneuraminic acid) were compared for their reactivity with Hanganutziu-Deicher (‘serum sickness’) antibodies by double-diffusion gel precipitation tests. Only N-glycolylneuraminic acid containing gangliosides formed precipitation lines with Hanganutziu-Deicher antibodies, thus suggesting that Hanganutziu-Deicher antigens are gangliosides that contain N-glycolylneuraminic acid.Keywords
This publication has 3 references indexed in Scilit:
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- Isolation and partial characterization of the heterophile antigen of infectious mononucleosis from bovine erythrocytesJournal of Supramolecular Structure, 1977
- The Thiobarbituric Acid Assay of Sialic AcidsJournal of Biological Chemistry, 1959