Highly Chemoselective Copper-Catalyzed Conjugate Reduction of Stereochemically Labile α,β-Unsaturated Amino Ketones
- 9 September 2009
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 74 (19) , 7598-7601
Abstract
Highly chemoselective conjugate reduction of chiral α,β-unsaturated amino ketones has been developed by using triisopropyl phosphite ligated copper hydride complex. The highlights of the method are wide substrate compatibility and exceptional chemoselectivity.Keywords
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