Differential Diagnosis of Idiopathic Fibrosis from Malignant Lymphadenopathy with PET and F-18 Fluorodeoxyglucose

Authors:
  • KYKenji Yamada
    Kenji Yamada
  • SYSeiro Yoshioka
    Seiro Yoshioka
  • SYSusumu Yamada
    Susumu Yamada
  • MIMasatoshi Ito
    Masatoshi Ito
  • TITatsuo Ido
    Tatsuo Ido
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Abstract
Idiopathic fibrosis and malignant lymphoma were studied with positron emission tomography (PET) using 2-deoxy-2-[F-18]fluoro-D-glucose (F-18DG). Cases of retroperitoneal fibrosis and sclerosing peritonitis showed low F-18DG uptake with the mass/muscle radioactivity (M/M) ratio 2.0 and 1.9, respectively. A case of para-aortic adenopathy from malignant lymphoma showed high F-18DG uptake with the M/M ratio 9.4. F-18DG PET study may be useful for the differential diagnosis of idiopathic fibrosis and malignant lymphadenopathy.