Frontiers in Pigment Cell and Melanoma Research

Authors:
  • SBStanca Birlea
    Stanca Birlea
  • MBMarcus W. Bosenberg
    Marcus W. Bosenberg
  • DBDouglas Brash
    Douglas Brash
  • PCPamela B. Cassidy
    Pamela B. Cassidy
  • SCSuzie Chen
    Suzie Chen
  • JDJohn August D'Orazio
    John August D'Orazio
  • MFMayumi Fujita
    Mayumi Fujita
  • BGBoon-Kee Goh
    Boon-Kee Goh
  • MHMeenhard Herlyn
    Meenhard Herlyn
  • AIArup K. Indra
    Arup K. Indra
  • LLLionel Larue
    Lionel Larue
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Abstract
We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact current approaches to research in melanoma and the dermatological sciences. We focus on four themes: (1) clinical melanoma research, (2) basic melanoma research, (3) clinical dermatology, and (4) basic pigment cell research, with the goal of outlining current highlights, challenges, and frontiers associated with pigmentation and melanocyte biology. Significantly, this document encapsulates important advances in melanocyte and melanoma research including emerging frontiers in melanoma immunotherapy, medical and surgical oncology, dermatology, vitiligo, albinism, genomics and systems biology, epidemiology, pigment biophysics and chemistry, and evolution.

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