Regio‐ and Stereoselective Synthesis of Tri‐ and Tetrasubstituted Enamides via Palladium‐Catalyzed Silaboration of Ynamides
- 15 March 2013
- journal article
- research article
- Published by Wiley in Advanced Synthesis & Catalysis
- Vol. 355 (5) , 853-856
Abstract
The palladium‐catalyzed silaboration of ynamides is demonstrated. The silaboration proceeds in a highly regioselective manner to give the corresponding tri‐ and tetrasubstituted enamide derivatives having both a silyl group and a boryl group on the alkene. Furthermore, the silaborated enamide could be utilized as a coupling partner in Suzuki–Miyaura coupling with aryl iodides to give the corresponding cross‐coupling product in good yield.Keywords
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