Herpesviruses in Multiple Sclerosis
Author:
- Robert M. HerndonRHRobert M. Herndon
- 1 February 1996
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 53 (2) , 123-124
Abstract
In this issue of theArchives, Sanders et al1report on the presence of herpes simplex virus (HSV) 1 and 2 in 46% of postmortem brain tissue samples from patients with multiple sclerosis and in 28% of samples from control cases. In the August 1995 issue of theProceedings of the National Academy of Science, Challoner et al2report on the presence of human herpesvirus 6 (HHV-6) in brain samples from patients with MS. These two articles represent the latest among many reports of viruses detected in MS brain by culture, hybridization techniques, or immunocytochemical methods. Are these simply observations on the normal viral flora found in the brain, perhaps enhanced in the MS brains by the use of immunosuppressive agents and steroids? While the observations on HHV-6 have been met with underwhelming enthusiasm, there are a number of reasons why such observations deserve careful examination. See alsoKeywords
This publication has 3 references indexed in Scilit:
- Herpes Simplex Virus in Postmortem Multiple Sclerosis Brain TissueArchives of Neurology, 1996
- Dorsal root ganglia may be reservoirs of viral infection in multiple sclerosisMedical Hypotheses, 1993
- MULTIPLE SCLEROSIS: A FEVER BLISTER ON THE BRAIN?The Lancet, 1974