Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes

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Abstract
In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber membranes was characterized. A successful composite nanofiber membrane sample was observed by scanning electron microscopy (SEM). The addition of AuNPs showed the improved as well as prolonged cumulative release of the drug. The results indicated that PVDF–AuNPs nanofiber membrane could potentially be applied for nerve regeneration.
Funding Information
  • National Natural Science Foundation of China (81601596)
  • Key Research and Development Projects of Shaanxi (2020SF-423, 2020FP-029, 2021SF-339)
  • The Scientific Research Foundation for Youth Scholars of Xinyang Agricultural and Forestry University (2019LG011)

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