Successful outcome with aggressive treatment of acute haemorrhagic leukoencephalitis

Authors:
  • RMR Markus
    R Markus
  • BBB J Brew
    B J Brew
  • MPM Pell
    M Pell
  • TKTakeharu Kunieda
    Takeharu Kunieda
  • NMNobuhiro Mikuni
    Nobuhiro Mikuni
  • WTWaro Taki
    Waro Taki
  • JKJun Kimura
    Jun Kimura
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Abstract
OBJECTIVE To investigate somesthetic functions of the perisylvian cortex. Methods—Somatosensory evoked magnetic fields (SEFs) and somatosensory evoked potentials (SEPs) of the perisylvian cortex were recorded directly from subdural electrodes in a patient with a left frontal brain tumour. RESULTS The most prominent SEP components after electrical stimulation of the right and left hands and the right foot were double peaked negativity recorded just above the sylvian fissure (latency 80 to 150 ms), respectively (N1a and N1b). Generator sources for the magnetoencephalographic counterparts of those peaks (N1a(m) and N1b(m)) were both localised at the upper bank of the sylvian fissure, and those of N1a(m) were more anteromedially located than those of N1b(m). CONCLUSIONS These findings suggest the existence of at least two separate somatosensory areas within the human perisylvian cortex.